The blue type of Toothberries appear in their own level, Itty Bitty Biters, inside the Ruins world, as well as the Forest level Clingy Swingy. They are aggressive and will jump out of walls and panels in the floor. Blue Toothberries usually can be found in large groups, however they do not pursue the primates, they will just randomly leap around certain areas. They can be defeated by a single jump attack, roll attack or barrel throw. Blue Toothberries cannot be stunned by the ground-pound move and peanuts shot by Diddy Kong's Peanut Popguns.
Red Toothberries are larger, more aggressive, less common, and jump higher than their blue counterparts. They are slightly harder to beat than regular Toothberries due to the fact that they jump around and actively pursue the Kongs. Red Toothberries can be defeated by two jump attacks, a roll attack or throwing a barrel at them. They are also immune to the ground-pound move and peanut shots.
Acks, or Ackstacks, are another form of Toothberries who are colored yellow and are found only in stacks of five. As stacks, they are invincible to all Kongs' attacks, including the ground-pound move and Diddy Kong's Peanut Popguns. However, an entire stack can be instantly defeated by a barrel thrown at it. Upon seeing the heroes, Acks will throw themselves in an attempt to bite the primates. It leaves them very vulnerable with their mouths stuck in the ground. Even in this state, each individual Ack is still immune to all attacks, except for jump attacks. With all five of them lying on the ground it is rather easy for the player to earn some Banana Coins by bouncing over three or more of them consecutively.
Cageberries are blue Toothberries trapped in pointy cages. They are invincible to any attacks by the primates. If the Kongs ground-pound close by, roll into them or throw a barrel at them, the Cageberries will turn upside-down, and get stunned briefly. It allows the heroes to step on the cages. By the primates pounding on the cage base two times, after the cage is buried on the ground, the Cageberries will throw the Kongs high into the air, allowing them to reach items and platforms.
- Many statues sculpted after the Toothberries and their variants can be seen, and some of them can be broken by the ground-pound move, in the Ruins level Itty Bitty Biters of the games Donkey Kong Country Returns and Donkey Kong Country Returns 3D.
- These statues could indicate that the enemies have been inside the ruins of the same level for some considerable time.
- It can be speculated that whoever build the same statues feared and/or worshipped the Toothberries.
- The Toothberries and their variants' overall design, a round shape covered in fur, and tiny, sharp teeth, resembles Krites, evil carnivorous aliens, from the Critters franchise.